Nolatrexed dihydrochloride
Catalogue number:
HY-108474-5mg
Supplier:
Size:
5 mg _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
152946-68-4
Purity:
98.54
Molecular Formula:
C14H14Cl2N4OS
Molecular Weight:
357.26
Alternative Names:
AG 337; Thymitaq
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Nolatrexed dihydrochloride (AG 337) is a non-competitive lipophilic inhibitor of thymidylate synthase, interacts at the folate cofactor binding site of the enzyme, with a Ki of 11 nM for human thymidylate synthase[1]. Nolatrexed dihydrochloride (AG 337) induces cell cycle arrest in S phase of cancer cells. Anti-cancer activity[2].
Storage Temperature:
-20°C (Powder, sealed storage, away from moisture)