This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2088323-16-2
Purity:
99.15
Molecular Formula:
C26H32N8O3
Molecular Weight:
504.58
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
TAS0728 is a potent, selective, orally active, irreversible and covalent-binding HER2 inhibitor, with an IC50 of 13 nM. TAS0728 also shows IC50s of 4.9, 8.5, 31, 65, 33, 25 and 86 nM for BMX、HER4、BLK、EGFR、JAK3、SLK and LOK respectively. Furthermore, TAS0728 exhibits robust and sustained inhibition of the phosphorylation of HER2[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)