This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1610964-64-1
Purity:
99.45
Molecular Formula:
C19H13F5N6
Molecular Weight:
420.34
Alternative Names:
PTC596
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Unesbulin (PTC596) is an orally active and selective B-cell-specific Moloney murine leukemia virus integration site 1 (BMI-1) inhibitor. Unesbulin downregulates MCL-1 and induces p53-independent mitochondrial apoptosis in acute myeloid leukemia (AML) cells. Unesbulin has anti-leukemic activity[1][2].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)