This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2052128-15-9
Purity:
98
Molecular Formula:
C31H34N4O2
Molecular Weight:
494.63
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
H3B-5942 is a selective, irreversible and orally active estrogen receptor covalent antagonist, inactivates both wild-type and mutant ERα by targeting Cys530, with Kis of 1 nM and 0.41 nM, respectively. H3B-5942 reduces ERα target gene GREB1, shows potent antitumor activity both in multiple cell lines or animals bearing ERαWT or ERα mutations[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)