This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2262452-06-0
Purity:
99.89
Molecular Formula:
C19H12Cl2N4O3
Molecular Weight:
415.23
Alternative Names:
RU320521
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
RU.521 (RU320521) is a potent and selective cyclic GMP-AMP synthase (cGAS) inhibitor and inhibits cGAS-mediated interferon upregulation. RU.521 suppresses dsDNA-activated reporter activity with an IC50 of 0.7 µM. RU.521 reduces constitutive expression of interferon in macrophages from a mouse model of Aicardi-Goutières syndrome (AGS)[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)