This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1646839-59-9
Purity:
98.07
Molecular Formula:
C32H26N4O6
Molecular Weight:
562.57
Alternative Names:
ONO-7475
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Tamnorzatinib (ONO-7475) is a potent, selective, and orally active Axl/Mer inhibitor with IC50 values of 0.7 nM and 1.0 nM, respectively. Tamnorzatinib sensitizes AXL-overexpressing EGFR-mutant NSCLC cells to the EGFR-TKIs, suppresses the emergence and maintenance of tolerant cells. Tamnorzatinib combines with Osimertinib (HY-15772) provides a bright promise for the study of EGFR-mutated non-small cell lung cancer (NSCLC).
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)