Deucravacitinib
Catalogue number:
HY-117287-25mg
Supplier:
Size:
25 mg _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1609392-27-9
Purity:
99.87
Molecular Weight:
425.46
Alternative Names:
BMS-986165
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Deucravacitinib (BMS-986165) is a highly selective, orally bioavailable allosteric TYK2 inhibitor for the treatment of autoimmune diseases, which selectively binds to TYK2 pseudokinase (JH2) domain (IC50=1.0 nM) and blocks receptor-mediated Tyk2 activation by stabilizing the regulatory JH2 domain. Deucravacitinib inhibits IL-12/23 and type I IFN pathways. Deucravacitinib, the FDA's world first de novo deuterium, is available for study in moderate to severe plaque psoriasis[1][2].
Storage Temperature:
-20°C, 3 years (Powder)