This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1642303-38-5
Purity:
99.58
Molecular Weight:
605.56
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
ITI-214 is a potent, CNS-active, orally bioavailable PDE1 inhibitor (Ki of 58 pM) with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters and ion channels. ITI-214 inhibits recombinant full-length human PDE1A, PDE1B and PDE1C with Kis of 33 pM, 380 pM and 35 pM, respectively. ITI-214 shows efficacy in various animal models of motor and cognitive functions[1][2].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture)