This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1216941-48-8
Purity:
99.89
Molecular Weight:
765.88
Alternative Names:
ABT-450; Veruprevir
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Paritaprevir (ABT-450) is a potent, orally active and antiviral non-structural protein 3/4A (NS3/4A) protease inhibitor with EC50s of 1 and 0.21 nM against HCV 1a and 1b, respectively. Paritaprevir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.31 µM. Paritaprevir is metabolized primarily by cytochrome P450 (CYP) 3A. The plasma concentration and half-life of Paritaprevir can be enhanced by Ritonavir (a CYP450 inhibitor)[1][2][3][4].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture and light)