5-(N,N-Hexamethylene)-amiloride
Catalogue number:
HY-128067-10mg
Supplier:
Size:
10 mg _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1428-95-1
Purity:
98.47
Molecular Weight:
311.77
Alternative Names:
Hexamethylene amiloride; HMA
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) derives from an amiloride and is a potent Na+/H+ exchanger inhibitor, which decreases the intracellular pH (pHi) and induces apoptosis in leukemic cells. 5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) is also an inhibitor of the HIV-1 Vpu virus ion channel and inhibits mouse hepatitis virus (MHV) replication and human coronavirus 229E (HCoV229E) replication in cultured L929 cells with EC50s of 3.91 µM and 1.34 µM, respectively[1][2].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)