Belnacasan
Catalogue number:
HY-13205-50mg
Supplier:
Size:
50 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
273404-37-8
Purity:
99.99
Molecular Weight:
509
Alternative Names:
VX-765
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Belnacasan (VX-765) is an orally bioactive proagent of VRT-043198, which is a potent and selective inhibitor of IL-converting enzyme (ICE)/caspase-1 with Kis of 0.8 nM and less than 0.6 nM for caspase-1 and caspase-4, respectively. Belnacasan (VX-765) inhibits the release of LPS-induced IL-1β and IL-18 by human PBMCs with an IC50 of ~0.7 µM[1][2].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)