AZD3839 (free base)
Catalogue number:
HY-13438-1mL
Supplier:
Size:
1 ml
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1227163-84-9
Purity:
99.98
Molecular Weight:
431.41
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
AZD3839 free base is a potent and selective orally active, brain-permeable BACE1 inhibitor (Ki=26 nM). AZD3839 free base shows 14 and >1000-fold selectivity against BACE2 and cathepsin D, respectively. AZD3839 free base exhibits dose- and time-dependent lowering of plasma, brain, and cerebrospinal fluid Aβ levels in mouse, guinea pig, and non-human primate. AZD3839 free base can be used for the research of Alzheimer's disease[1][2].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)