TAK-285
Catalogue number:
HY-15196-5mg
Supplier:
Size:
5 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
871026-44-7
Purity:
99.7
Molecular Weight:
547.96
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
TAK-285 is a potent, selective, ATP-competitive and orally active HER2 and EGFR(HER1) inhibitor with IC50 of 17 nM and 23 nM, respectively. TAK-285 is >10-fold selectivity for HER1/2 than HER4, and less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. TAK-285 has effective antitumor activity[1]. TAK-285 can cross the blood-brain barrier (BBB)[2].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)