Osilodrostat
Catalogue number:
HY-16276-25mg
Supplier:
Size:
25 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
928134-65-0
Purity:
99.9
Molecular Weight:
227.24
Alternative Names:
LCI699
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Osilodrostat (LCI699) is a potent, orally active11β-hydroxylase (CYP11B1) inhibitor with an IC50 value of 35 nM. Osilodrostat is a potent, orally aldosterone synthase (CYP11B2) inhibitor with IC50 values of 0.7 nM and 160 nM for human aldosterone synthase and rat aldosterone synthase, respectively. Osilodrostat inhibits aldosterone and corticosterone synthesis. Osilodrostat has blood pressure lowering ability. Osilodrostat can be used for research of Cushing syndrome (CS)[1][2][3].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)