S1RA (hydrochloride)
Catalogue number:
HY-18099A-5mg
Supplier:
Size:
5 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1265917-14-3
Purity:
99.85
Molecular Weight:
373.88
Alternative Names:
E-52862 hydrochloride
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
S1RA (E-52862) hydrochloride is an orally active and selective sigma-1 receptor (σ1R) antagonist with a Ki value of 17 nM. S1RA hydrochloride shows good selectivity against σ2R (Ki >1000 nM). S1RA hydrochloride is a human 5-HT2B receptor antagonist with an IC50 value of 4.7 µM. S1RA hydrochloride inhibits neuropathic pain and activity-induced spinal sensitization[1][2].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture)