BRD3308
Catalogue number:
HY-19618-5mg
Supplier:
Size:
5 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1550053-02-5
Purity:
98.07
Molecular Weight:
287.29
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
BRD3308 is a highly selective HDAC3 inhibitor with an IC50 of 54 nM. BRD3308 is 23-fold selectivity for HDAC3 over HDAC1 (IC50 of 1.26 µM) or HDAC2 (IC50 of 1.34 µM). BRD3308 suppresses pancreatic β-cell apoptosis induced by inflammatory cytokines or glucolipotoxic stress, and increases functional insulin release. BRD3308 activates HIV-1 transcription and disrupts HIV-1 latency[1][2][3].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)