This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
535-96-6
Purity:
99.49
Molecular Weight:
450.39
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Marein has the neuroprotective effect due to a reduction of damage to mitochondria function and activation of the AMPK signal pathway. Marein improves insulin resistance induced by high glucose in HepG2 cells through CaMKK/AMPK/GLUT1 to promote glucose uptake, through IRS/Akt/GSK-3β to increase glycogen synthesis, and through Akt/FoxO1 to decrease gluconeogenesis. Marein is a HDAC inhibitor with an IC50 of 100 µM. Marein has beneficial antioxidative, antihypertensive, antihyperlipidemic and antidiabetic effects[1][2][3].
Storage Temperature:
4°C (Powder, protect from light)