£295.00
Estimated delivery Wed 7 Aug
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
875158-73-9
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
428.6
Alternative Names:
2-(cyclohexylsulfonyl)-n,n-dimethyl-4-[(4-methylphenyl)sulfonyl]-5-thiazolamine
- Data sheet: View or download
- MSDS: View or download
Product Description:
A STING agonist; induces IFN reporter gene expression in HEK293T cells expressing wild-type human STING but not in HEK293T cells expressing the HAQ human STING variant nor in mouse RAW 264.7 cells at 75 µM; induces the production of TNF-α, IL-10, IL-1β, and IL-12p70 in human PBMCs; increases the percentage of isolated human monocyte-derived dendritic cells expressing HLA-DR, CD40, CD80, and CD86, as well as increases T cell cross-priming of the same cells in an ex vivo assay, at 50 µM
Storage Temperature:
-20°C