CB-6644
Catalogue number:
CAY36125-1 mg
Supplier:
Size:
1 mg
Product is available in:
£86.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2316817-88-4
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
573.1
Alternative Names:
5-chloro-n-[4-[[6,7-dihydro-3-(methoxymethyl)-1-oxo-1h,5h-pyrazolo[1,2-a][1,2]benzodiazepin-2-yl]amino]-2,2-dimethyl-4-oxobutyl]-2-ethoxy-4-fluoro-benzamide
- Data sheet: View or download
- MSDS: View or download
Product Description:
An inhibitor of the RUVBL1/2 complex (IC50 = 15 nM for the ATPase activity); selective for the RUVBL1/2 complex over a panel of 224 ATPases at 10 µM; reduces viability in a panel of cancer cell lines (EC50s = 41-785); induces apoptosis in HCT116 colon cancer cells at 0.4 µM; reduces tumor growth in Ramos Burkitt’s lymphoma and RPMI-8226 multiple myeloma xenograft mouse models at 150 mg/kg
Storage Temperature:
-20°C