Y-33075
Catalogue number:
CAY35108-5 mg
Supplier:
Size:
5 mg
Product is available in:
£479.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
199433-58-4
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
280.3
Alternative Names:
4-[(1r)-1-aminoethyl]-n-1h-pyrrolo[2,3-b]pyridin-4-yl-benzamide, rki-983, snj-1656, y-39983
- Data sheet: View or download
- MSDS: View or download
Product Description:
An inhibitor of ROCK2 (IC50 = 3.6 nM); selective for ROCK2 over PKC and CaMKII (IC50s = 420 and 810 nM, respectively); topical application reduces intraocular pressure in rabbit and cynomolgus monkeys at 0.05% v/v; increases axonal regeneration at the crush site in a cat model of surgically-induced optic nerve damage at 10 and 100 µM; inhibits demyelination and reduces the incidence of relapse episodes in a mouse model of chronic relapsing EAE
Storage Temperature:
-20°C