BMS-299897
Catalogue number:
CAY35777-5 mg
Supplier:
Size:
5 mg
Product is available in:
£147.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
290315-45-6
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
511.9
Alternative Names:
2-[(1r)-1-[[(4-chlorophenyl)sulfonyl](2,5-difluorophenyl)amino]ethyl]-5-fluoro-benzenebutanoic acid
- Data sheet: View or download
- MSDS: View or download
Product Description:
A γ-secretase inhibitor; selectively cleaves APP CTF over Notch-1 CTF in HEK293 cells (IC50s = 7.1 and 105.9 nM, respectively); reduces increases in Aβ42 levels induced by Aβ (25-35) in the mouse hippocampus at 0.1-1 nmol/animal; prevents deficits induced by Aβ (25-35) in the novel object recognition test when tested with a one-hour, but not a 24-hour, intertrial interval
Storage Temperature:
-20°C