GPR52 Comp-43
Catalogue number:
CAY33564-25 mg
Supplier:
Size:
25 mg
Product is available in:
£301.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1239987-91-7
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
242.3
Alternative Names:
(2e)-5-phenyl-1-(2-thienyl)-2-penten-1-one, gpr52-in-43
- Data sheet: View or download
- MSDS: View or download
Product Description:
A GPR52 antagonist (IC50 = 0.63 µM); reduces mHTT protein levels in STHdhQ7/Q111 cells in a concentration-dependent manner; reduces apoptosis induced by growth factor deprivation in primary striatal neurons isolated from HdhQ7/Q140 mice; decreases striatal levels of soluble and insoluble mHTT, as well as increases the latency to fall in the rotarod test, in the HdhQ140 mouse model of Huntington's disease at 5 mg/kg
Storage Temperature:
-20°C