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MHY553

Catalogue number:
CAY36088-25 mg
Supplier:
Size:
25 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£774.00 Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

6265-56-1

Purity:

≥98%

Formulation:

A solid

Molecular Weight:

243.3

Alternative Names:

4-(2-benzothiazolyl)-1,3-benzenediol, nsc 33005

Product Description:

An agonist of PPARα; activates PPARα in HepG2 cells in a reporter assay at 1 µM but does not activate PPARβ or PPARγ at 10 µM; prevents T0901317-induced triglyceride accumulation in HepG2 cells at 3 µM; scavenges ROS and peroxynitrite in cell-free assays (IC50s = 39.7 and 2.39 µM, respectively); inhibits β-glucuronidase and tyrosinase (IC50s = 8.9 and 0.01 µM for the bovine liver and mushroom enzymes, respectively); reduces age-induced increases in liver weight and triglyceride levels in a rat model of hepatic steatosis at 5 mg/kg

Storage Temperature:

-20°C

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