ERX-41
Catalogue number:
CAY37726-10 mg
Supplier:
Size:
10 mg
Product is available in:
£957.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2440087-54-5
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
704.8
Alternative Names:
4-[[3-(2-hydroxyethoxy)-4-nitrobenzoyl]amino]-n-[4-[[(trans-4-methylcyclohexyl)amino]carbonyl]-2-(2-methylpropoxy)phenyl]-3-(2-methylpropoxy)-benzamide
- Data sheet: View or download
- MSDS: View or download
Product Description:
An ER stress inducer; increases the thermal stability of lysosomal acid lipase at 10 µM in the CETSA but does not inhibit lysosomal acid lipase enzymatic activity at 30 µM; increases ER tubule width, EIF2AK3 and IRE1α phosphorylation, and XBP1 splicing in SUM149 cells at 1 µM; reduces tumor volume and weight in several PDX mouse models of TNBC at 10 mg/kg
Storage Temperature:
-20°C