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PGS-IN-1

Catalogue number:
CAY37666-10 mg
Supplier:
Size:
10 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£283.00 Estimated delivery Fri 9 Aug
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

102271-49-8

Purity:

≥95%

Formulation:

A solid

Molecular Weight:

302.4

Alternative Names:

(e)-3-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]dihydro-2(3h)-furanone, kme-4, pg synthetase inhibitor 1, pgs inhibitor 1, prostaglandin synthetase inhibitor 1

Product Description:

An NSAID and a dual inhibitor of COX and 5-LO (IC50s = 0.44 and 0.85 µM, respectively); selective for 5-LO over 12-LO (IC50 = >100 µM for 12-LO for the rabbit enzyme); inhibits paw swelling and bone damage in a rat model of M. butyricum-induced arthritis at 10 mg/kg per day, p.o.

Storage Temperature:

-20°C

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