MBQ-167
Catalogue number:
CAY35437-1 mg
Supplier:
Size:
1 mg
Product is available in:
£39.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2097938-73-1
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
338.4
Alternative Names:
9-ethyl-3-(5-phenyl-1h-1,2,3-triazol-1-yl)-9h-carbazole
- Data sheet: View or download
- MSDS: View or download
Product Description:
A dual inhibitor of Rac and Cdc42 (IC50s = 103 and 78 nM, respectively); reduces Rac and Cdc42 GTP-binding and GTPase activity and limits migration and mammosphere formation in MDA-MB-231 cells at 250 nM; reduces cell viability and induces apoptosis at 250 nM in lapatinib-resistant SK-BR-3 and MDA-MB-435 cells alone or with lapatinib; reduces growth rates, axial budding, and Cdc42 activity in S. cerevisiae at 200 µM; reduces tumor growth in an MDA-MB-435 mouse xenograft model at 1 or 10 mg/kg three times per week, i.p.
Storage Temperature:
-20°C