Dot1L-IN-1 (TFA)
Catalogue number:
HY-101520A-1mg
Supplier:
Size:
1 mg _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
Purity:
98.56
Molecular Formula:
C34H37ClF3N9O4S
Molecular Weight:
760.23
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Dot1L-IN-1 TFA is a highly potent and selective Dot1L inhibitor with a Ki of 2 pM and an IC50 of <0.1 nM. Dot1L-IN-1 TFA potently suppresses H3K79 dimethylation (IC50=3 nM), as well as the activity of the HoxA9 promoter (IC50=17 nM) in HeLa and Molm-13 cells, respectively[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)