This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
362505-84-8
Purity:
99.99
Molecular Formula:
C27H32N4O6S
Molecular Weight:
540.63
Alternative Names:
SB-462795
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Relacatib (SB-462795) is a novel, potent, and orally active inhibitor of human cathepsins K, L, and V with Ki values of 41 pM, 68 pM, and 53 pM, respectively. Relacatib inhibits endogenous cathepsin K in situ in human osteoclasts and human osteoclast-mediated bone resorption with IC50 values of 45 nM and 70 nM, respectively. Relacatib inhibits bone resorption in vitro in human tissue as well as in cynomolgus monkeys in vivo[1][2].
Storage Temperature:
4°C (Powder, protect from light, stored under nitrogen)