This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1586787-08-7
Purity:
99.05
Molecular Formula:
C25H33N3O3S
Molecular Weight:
455.61
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
CMF019 is a potent and small molecule agonist at Apelin receptor (APJ) with G protein bias. CMF019 binds to APJ with pKi values of 8.58, 8.49 and 8.71 for human, rat, and mouse, respectively. CMF019 mimics the beneficial cardiovascular actions of apelin in rodents[1]. Apelin receptor (APJ) is a G protein-coupled receptor (GPCR) activated by the endogenous peptide apelin[2].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)