This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
241127-58-2
Purity:
99.02
Molecular Formula:
C24H27NO4
Molecular Weight:
393.48
Alternative Names:
NSC 680410
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Adaphostin (NSC 680410), the adamantyl ester of AG957, is a potent p210bcr/abl inhibitor (IC50=14 µM). Adaphostin induces apoptosis in T-lymphoblastic human leukemia cell lines (IC50 ranging from 17 to 216 nM). Adaphostin has significant and selective activity against chronic and acute myeloid leukemia cells. Adaphostin increased the level of reactive oxygen species (ROS) within CLL B cells[1][2][3].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)