This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1346233-68-8
Purity:
99.49
Molecular Formula:
C19H26Cl2N2O
Molecular Weight:
369.33
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
ML218 is a potent, selective and orally active T-type Ca2+ channels (Cav3.1, Cav3.2, Cav3.3) inhibitor with IC50s of 310 nM and 270 nM for Cav3.2 and Cav3.3, respectively. ML218 inhibits the burst activity in subthalamic nucleus (STN) neurons. ML218 has no significant inhibition of L- or N-type calcium channels, KATP or hERG potassium channels. ML218 can penetrate the blood-brain barrier[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)