AMN082 (free base)
Catalogue number:
HY-103565A-25mg
Supplier:
Size:
25 mg _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
83027-13-8
Purity:
99.07
Molecular Formula:
C28H28N2
Molecular Weight:
392.54
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
AMN082 free base, a selective, orally active, and brain penetrant mGluR7 agonist, directly activates receptor signaling via an allosteric site in the transmembrane domain. AMN082 free base potently inhibits cAMP accumulation and stimulates GTPγS binding (EC50 values, 64-290 nM) at transfected mammalian cells expressing mGluR7. AMN082 free base shows selectivity over other mGluR subtypes and selected ionotropic glutamate receptors. Antidepressant effects[1][2].
Storage Temperature:
4°C (Powder, protect from light)