3-Hydroxy Midostaurin
Catalogue number:
HY-108263-1mg
Supplier:
Size:
1 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
179237-49-1
Purity:
97.02
Molecular Weight:
586.64
Alternative Names:
CGP52421
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
3-Hydroxy Midostaurin (CGP 52421), a metabolite of PKC412, effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50s of approximately 132 nM and 9.8 µM in culture medium and plasma, respectively. 3-Hydroxy Midostaurin is less selective but more cytotoxic than PKC412[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)