JW67
Catalogue number:
HY-108442-10mg
Supplier:
Size:
10 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
442644-28-2
Purity:
98.06
Molecular Weight:
394.38
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
JW67 inhibits the canonical Wnt signaling with an IC50 of 1.17µM[1]. JW67 affects the multiprotein complex consisting of β-catenin/GSK-3β/AXIN/APC/CK1 that rapidly reduces active β-catenin with a subsequent downregulation of Wnt target genes. JW67 also inhibits colorectal cancer cell growth[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)