This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
104869-26-3
Purity:
92
Molecular Weight:
1437.1
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
NF157 is a highly selective nanomolar P2Y11 antagonist with a pKi of 7.35. The IC50s are 463 nM, 1811 µM, 170 µM for P2Y11 (Ki=44.3 nM), P2Y1 (Ki=187 µM), P2Y2 (Ki=28.9 µM), respectively[1]. NF157, significantly reduces expression of metalloproteinase (MMP)-3, MMP-13, can be used in the treatment of osteoarthritis (OA)[2].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture)