This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
942655-44-9
Purity:
99.72
Molecular Weight:
323.35
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
JK-P3 is a potent and pan VEGFR2 inhibitor, with IC50s of 7.83 µM, 27 µM and 5.18 µM for VEGFR2, FGFR1 and FGFR3, respectively. JK-P3 can inhibit VEGF-A-stimulated VEGFR2 activation and intracellular signalling, also inhibits endothelial monolayer wound closure and angiogenesis, as well as fibroblast growth factor receptor kinase activity in vitro. JK-P3 has anti-angiogenic activity[1].
Storage Temperature:
4°C (Powder, protect from light)