This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1971920-73-6
Purity:
98.96
Molecular Weight:
455.51
Alternative Names:
SAR442168; PRN2246
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Tolebrutinib (SAR442168) is a potent, selective, orally active and brain-penetrant inhibitor of Bruton tyrosine kinase (BTK), with IC50s of 0.4 and 0.7 nM in Ramos B cells and in HMC microglia cells, respectively. Tolebrutinib exhibits efficacy in central nervous system immunity. Tolebrutinib can be used for the research of multiple sclerosis (MS)[1][2].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)