This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1832713-02-6
Purity:
98.9
Molecular Weight:
452.57
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
RA839 is a noncovalent small molecule binder to Keap1 with a Kd of ∼6 µM and selective activator of Nrf2 signaling. RA839 prevents the induction of both inducible nitric-oxide synthase expression and nitric oxide release in response to lipopolysaccharides in macrophages. RA839 is a selective inhibitor of the Keap1/Nrf2 interaction and a useful tool compound to study the biology of Nrf2[1].
Storage Temperature:
4°C (Powder, protect from light)