This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1417630-95-5
Purity:
99.51
Molecular Weight:
474.56
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
PIM1-IN-1 is a potent and highly selective PIM1/3 inhibitor, with IC50s of 7, 5530 and 70 nM for PIM1, PIM2, and PIM3, respectively, inhibits the phosphorylation of BAD, a downstream target of PIM, with an EC50 of 262 nM. PIM1-IN-1 shows no obvious effect on FLT3 or hERG binding. Antiproliferative and anti-cancer activity[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)