This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2763260-39-3
Purity:
99.07
Molecular Weight:
510.32
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
NRX-252114 is a potent enhancer of the interaction between β-catenin, and its cognate E3 ligase, SCFβ-TrCP. NRX-252114 enhances the binding of pSer33/S37A β-catenin peptide for β-TrCP with an EC50 of 6.5 nM and a Kd of 0.4 nM. NRX-252114 induces mutant β-catenin degradation[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)