This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
823828-18-8
Purity:
97
Molecular Weight:
433.45
Alternative Names:
CPD188
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
C188 is a STAT3 inhibitor that inhibits IL-6-stimulated STAT3 phosphorylation and nuclear translocation in HepG2 cells by targeting STAT3 SH2 domain peptide-binding pocket. C188, in particular, was highly active in inducing apoptosis of the breast cancer cell line MB-MDA-468 in vitro (EC50= 0.7 µM).
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)