Ivarmacitinib
Catalogue number:
HY-112724-25mg
Supplier:
Size:
25 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1445987-21-2
Purity:
99.82
Molecular Weight:
414.48
Alternative Names:
SHR0302
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Ivarmacitinib (SHR0302) is a potent and orally active all members of the JAK family inhibitor, particularly JAK1. The selectivity of Ivarmacitinib for JAK1 is >10-fold for JAK2, 77-fold for JAK3, 420-fold for Tyk2. Ivarmacitinib inhibits JAK1-STAT3 phosphorylation and induces the apoptosis of hepatic stellate cells. Ivarmacitinib has anti-proliferative and anti-inflammatory effects[1][2].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)