Almonertinib (mesylate)
Catalogue number:
HY-112823A-25mg
Supplier:
Size:
25 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2134096-06-1
Purity:
99.85
Molecular Weight:
621.75
Alternative Names:
HS-10296 (mesylate)
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Almonertinib (HS-10296) mesylate is an orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor with high selectivity for EGFR-sensitizing and T790M resistance mutations. Almonertinib mesylate shows great inhibitory activity against T790M, T790M/L858R and T790M/Del19 (IC50: 0.37, 0.29 and 0.21 nM, respectively), and is less effective against wild type (3.39 nM). Almonertinib mesylate is used for the research of the non-small cell lung cancer[1][2].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture)