This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
217798-39-5
Purity:
98
Molecular Formula:
C16H12N2O2Se2
Molecular Weight:
422.2
Alternative Names:
BBSKE
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Ethaselen (BBSKE) is an orally active, selective thioredoxin reductase (TrxR) inhibitor with IC50s of 0.5 and 0.35 µM for the wild-type human TrxR1 and rat TrxR1, respectively. Ethaselen specifically binds to the unique selenocysteine-cysteine redox pair in the C-terminal active site of mammalian TrxR1. Ethaselen, an organoselenium compound, is a potent antitumor candidate that exerts potent inhibition on non-small cell lung cancer (NSCLC) by targeting TrxR[1][2].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)