AKN-028 (acetate)
Catalogue number:
HY-118304B-50mg
Supplier:
Size:
50 mg _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
Purity:
99.95
Molecular Formula:
C19H18N6O2
Molecular Weight:
362.39
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
AKN-028 acetate, a novel tyrosine kinase (TK) inhibitor, is a potent, orally active FMS-like receptor tyrosine kinase 3 (FLT3) inhibitor with an IC50 value of 6 nM. AKN-028 acetate inhibits FLT3 autophosphorylation. AKN-028 acetate induces dose-dependent cytotoxic response (mean IC50=1 µM). AKN-028 acetate induces apoptosisby activation of caspase 3. AKN-028 acetate can be used in research of acute myeloid leukemia (AML).
Storage Temperature:
4°C (Powder, sealed storage, away from moisture)