This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1310012-12-4
Purity:
98.07
Molecular Weight:
294.32
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
VU0360172 is a potent and selective mGlu5 receptor positive allosteric modulator with an EC50 value of 16 nM and a Ki of 195 nM, respectively. VU0360172 stimulates polyphosphoinositide (PI) hydrolysis in vivo, which is abrogated in mGlu5 receptors gene deleted mice[1]. VU0360172 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Storage Temperature:
4°C (Powder, protect from light)