This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2229037-04-9
Purity:
98.06
Molecular Weight:
961.48
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
TL13-12 is a potent and selective ALK-PROTAC degrader and inhibits ALK activity with an IC50 value of 0.69 nM. TL13-12 also prompts the degradation of additional kinases including Aurora A, FER, PTK2, and RPS6KA1 with IC50 values of 13.5 nM, 5.74 nM, 18.4 nM, and 65 nM, respectively. TL13-12 is comprised of the conjugation of TAE684 (HY-10192) and the Cereblon ligand of Pomalidomide (HY-10984)[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)