CSRM617 (hydrochloride)
Catalogue number:
HY-122611A-5mg
Supplier:
Size:
5 mg _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1353749-74-2
Purity:
99
Molecular Weight:
291.69
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
CSRM617 hydrochloride is a selective small-molecule inhibitor of the transcription factor ONECUT2 (OC2, a master regulator of androgen receptor) with a Kd of 7.43 uM in SPR assays, binding to OC2-HOX domain directly. CSRM617 hydrochloride induces apoptosis by appearance of cleaved Caspase-3 and PARP. CSRM617 hydrochloride is well tolerated in the prostate cancer mouse model[1]
Storage Temperature:
-20°C (Powder, sealed storage, away from moisture)