GNE-0439
Catalogue number:
HY-123824-10mg
Supplier:
Size:
10 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1241902-40-8
Purity:
99.8
Molecular Weight:
345.48
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
GNE-0439 is a novel Nav1.7-selective inhibitor with IC50 of 0.34 uM and inhibits Nav1.5 with an IC50 of 38.3 µM. GNE-0439 inhibits mutant N1742K channels (IC50=0.37 uM) in membrane potential assays. GNE-0439 possesses a carboxylic acid group, binds outside of the channel pore, and is unique compared with known selective VSD4 binders[1].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture)