TL13-112
Catalogue number:
HY-123919-50mg
Supplier:
Size:
50 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2229037-19-6
Purity:
98.15
Molecular Weight:
1002.57
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
TL13-112 is a potent and selective ALK-PROTAC degrader and inhibits ALK activity with an IC50 value of 0.14 nM. TL13-112 also prompts the degradation of additional kinases including Aurora A, FER, PTK2 and RPS6KA1 with IC50 values of 8550 nM, 42.4 nM, 25.4 nM, and 677 nM, respectively. TL13-112 is comprised of the conjugation of Ceritinib (HY-15656) and the Cereblon ligand of Pomalidomide (HY-10984)[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)